Becky Davis

Becky Davis

@beckydavis

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2025-12-31 06:34:29 · Translate ·

Comprehensive Guide to Linker-Payload Design Strategies in ADC Project

Linker-payload design is a critical aspect of antibody-drug conjugate (ADC) development, directly determining the stability, targeting ability, and therapeutic efficacy of the drug in vivo. With the advancement of targeted therapies and precise drug delivery technologies, scientists are increasingly focusing on the chemical compatibility, spatial configuration, and pharmacokinetic...

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2025-12-31 06:32:05 · Translate ·

What is CRISPR-Cas9 in Gene Editing

The CRISPR-Cas system is a natural immune system in prokaryotes. Some bacteria, upon being invaded by viruses, can store a small segment of the viral genes in a region within their DNA known as CRISPR. Upon encountering the virus again, the bacteria can recognize the virus based on the stored segment, enabling them to cleave the viral DNA, rendering it ineffective. The invading...

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2025-12-31 06:31:07 · Translate ·

Strategies for Incorporating Unnatural Amino Acids into Proteins

Incorporating unnatural amino acids into proteins is a core strategy in modern protein engineering and chemical biology research. By introducing unnatural amino acids (UAAs) with specialized functions into protein molecules, researchers can achieve precise control over protein structure, activity, and function. This technology not only expands the chemical diversity of proteins but also opens...

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