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Rainbow Trout Hepatocytes to Advance Toxicology and Metabolism Research
Metabolic stability is a key factor to consider in the early stages of drug discovery. Even if a compound possesses promising pharmacological properties, it will never become a drug if it has poor metabolic stability. For instance, if a drug is rapidly metabolized in vivo, exposure levels may be insufficient, which could lead to the formation of toxic, inactive or active metabolites....
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